Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human brain tissue using Potassium Channel Kv3.2b antibody.)

Rabbit Potassium Channel Kv3.2b Polyclonal Antibody | anti-KCNC2 antibody

Potassium Channel Kv3.2b Antibody

Gene Names
KCNC2; KV3.2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Potassium Channel Kv3.2b; Polyclonal Antibody; Potassium Channel Kv3.2b Antibody; POTASSIUM CHANNEL; VOLTAGE-GATED; SHAW-RELATED SUBFAMILY; MEMBER 2; anti-KCNC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total Potassium Channel Kv3.2b protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
618
Applicable Applications for anti-KCNC2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from human Potassium Channel Kv3.
Target Name
Potassium Channel Kv3.2b
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human brain tissue using Potassium Channel Kv3.2b antibody.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human brain tissue using Potassium Channel Kv3.2b antibody.)

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, using Potassium Channel Kv3.2b antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, using Potassium Channel Kv3.2b antibody.)

Western Blot (WB)

(Western blot analysis of extracts from 293 cells (Lane 2), using Potassium Channel Kv3.2b antiobdy. The lane on the left is treated with synthesized peptide.)

Western Blot (WB) (Western blot analysis of extracts from 293 cells (Lane 2), using Potassium Channel Kv3.2b antiobdy. The lane on the left is treated with synthesized peptide.)
Related Product Information for anti-KCNC2 antibody
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channel properties are modulated by subunit assembly By similarity.Lizhen Yan, Mol. Pharmacol., May 2005; 67: 1513 - 1521. Bart A. Jessen, Toxicol. Sci., Sep 2003; 75: 208 - 222. Qingwei Deng, J. Neurosci., Dec 2005; 25: 11531 - 11541. Shuk Yin M. Yeung, J. Neurosci., Sep 2005; 25: 8735 - 8745.
Product Categories/Family for anti-KCNC2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68,317 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily C member 2 isoform 4
NCBI Official Synonym Full Names
potassium channel, voltage gated Shaw related subfamily C, member 2
NCBI Official Symbol
KCNC2
NCBI Official Synonym Symbols
KV3.2
NCBI Protein Information
potassium voltage-gated channel subfamily C member 2
UniProt Protein Name
Potassium voltage-gated channel subfamily C member 2
UniProt Gene Name
KCNC2
UniProt Entry Name
KCNC2_HUMAN

NCBI Description

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Uniprot Description

KCNC2: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channel properties are modulated by subunit assembly. Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.2/KCNC2 sub-subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q14.1

Cellular Component: voltage-gated potassium channel complex; integral to membrane; plasma membrane

Molecular Function: delayed rectifier potassium channel activity

Biological Process: synaptic transmission; regulation of action potential; energy reserve metabolic process; regulation of insulin secretion; protein homooligomerization

Research Articles on KCNC2

Similar Products

Product Notes

The KCNC2 kcnc2 (Catalog #AAA9402134) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Potassium Channel Kv3.2b Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Potassium Channel Kv3.2b can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the KCNC2 kcnc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Potassium Channel Kv3.2b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.