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Western Blot (WB) (Western Blot analysis of PPM1K expression in transfected 293T cell line by PPM1K polyclonal antibody. A: Non-transfected lysate. B: PPM1K transfected lysate. 12% SDS PAGEPrimary antibody diluted at 1: 500)

Rabbit anti-Human PPM1K Polyclonal Antibody | anti-PPM1K antibody

PPM1K antibody

Gene Names
PPM1K; BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Purified by antigen-affinity chromatography.
Synonyms
PPM1K; Polyclonal Antibody; PPM1K antibody; DKFZp667B084; anti-PPM1K antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
372
Applicable Applications for anti-PPM1K antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 334 of Human PPM1K
Target Name
PPM1K
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Western Blot (WB)

(Western Blot analysis of PPM1K expression in transfected 293T cell line by PPM1K polyclonal antibody. A: Non-transfected lysate. B: PPM1K transfected lysate. 12% SDS PAGEPrimary antibody diluted at 1: 500)

Western Blot (WB) (Western Blot analysis of PPM1K expression in transfected 293T cell line by PPM1K polyclonal antibody. A: Non-transfected lysate. B: PPM1K transfected lysate. 12% SDS PAGEPrimary antibody diluted at 1: 500)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded endo mitral OVCA, using PPM1K antibody at 1: 100 dilution.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded endo mitral OVCA, using PPM1K antibody at 1: 100 dilution.)
Product Categories/Family for anti-PPM1K antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,759 Da
NCBI Official Full Name
protein phosphatase 1K, mitochondrial
NCBI Official Synonym Full Names
protein phosphatase, Mg2+/Mn2+ dependent, 1K
NCBI Official Symbol
PPM1K
NCBI Official Synonym Symbols
BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07
NCBI Protein Information
protein phosphatase 1K, mitochondrial
UniProt Protein Name
Protein phosphatase 1K, mitochondrial
Protein Family
UniProt Gene Name
PPM1K
UniProt Synonym Gene Names
PP2CM; PTMP; PP2C-kappa
UniProt Entry Name
PPM1K_HUMAN

NCBI Description

This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012]

Uniprot Description

PPM1K: Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. Belongs to the PP2C family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: mitochondrial matrix

Molecular Function: metal ion binding; protein serine/threonine phosphatase activity

Biological Process: protein amino acid dephosphorylation

Disease: Maple Syrup Urine Disease, Mild Variant

Research Articles on PPM1K

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Product Notes

The PPM1K ppm1k (Catalog #AAA9401292) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPM1K antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPM1K can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250. Researchers should empirically determine the suitability of the PPM1K ppm1k for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPM1K, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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