Testing Data
Rabbit anti-Human ADAMTS3 Polyclonal Antibody | anti-ADAMTS3 antibody
ADAMTS3 Antibody
WB: 1:2000
Testing Data
Testing Data
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq, Jul 2008]
Uniprot Description
ADAMTS3: Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens.
Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.24.-; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; extracellular region
Molecular Function: heparin binding; protein binding; zinc ion binding; metalloendopeptidase activity; endopeptidase activity
Biological Process: collagen catabolic process; extracellular matrix organization and biogenesis; collagen fibril organization; fibril organization and biogenesis; protein processing; proteolysis; collagen biosynthetic process
Research Articles on ADAMTS3
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Product Notes
The ADAMTS3 adamts3 (Catalog #AAA9400972) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADAMTS3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADAMTS3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:2000 WB: 1:2000. Researchers should empirically determine the suitability of the ADAMTS3 adamts3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAMTS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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