Rat Eukaryotic Translation Initiation Factor 4E (EIF4E) ELISA Kit | EIF4E elisa kit
Rat Eukaryotic Translation Initiation Factor 4E (EIF4E) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
binds to the mRNA 7-methylguanosine cap and mediates mRNA binding to the 40S ribosome in the rate limiting step in translational initiation [RGD, Feb 2006]
Uniprot Description
EIF4E: a protein of the eukaryotic initiation factor 4E family. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the EIF4F complex.
Protein type: Translation initiation; Translation
Cellular Component: cytoplasm; eukaryotic translation initiation factor 4F complex; mRNA cap complex; perinuclear region of cytoplasm; protein complex; stress granule
Molecular Function: enzyme binding; eukaryotic initiation factor 4G binding; protein binding; translation initiation factor activity
Biological Process: behavioral fear response; G1/S transition of mitotic cell cycle; lung development; negative regulation of neuron differentiation; negative regulation of translation; positive regulation of mitotic cell cycle; regulation of translation; stem cell maintenance; translational initiation
Research Articles on EIF4E
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Product Notes
The Rat EIF4E eif4e (Catalog #AAA9352700) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9352700 ELISA Kit recognizes Rat EIF4E. It is sometimes possible for the material contained within the vial of "Eukaryotic Translation Initiation Factor 4E (EIF4E), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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