Rat p21 protein (Cdc42/Rac) -activated kinase 3 ELISA Kit | PAK3 elisa kit
Rat Serine/threonine-protein kinase PAK 3, PAK3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
displays GTP-p21 mediated protein kinase activity [RGD, Feb 2006]
Uniprot Description
PAK3: a protein kinase of the STE20 family that regulates synapse formation and plasticity in the hippocampus. May be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Forms an activated complex with GTP-bound P21, CDC2 and RAC1 proteins. Missense and truncation mutations linked to nonsyndromic mental retardation type 30 (MRX30). Two alternatively spliced human isoforms have been reported.
Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, STE; Kinase, protein; STE group; STE20 family; PAKA subfamily
Cellular Component: endosome
Molecular Function: MAP kinase kinase activity; protein serine/threonine kinase activity; GTPase binding; Rho GTPase binding; metal ion binding; SH3 domain binding; ATP binding; receptor signaling protein serine/threonine kinase activity; protein kinase activity
Biological Process: regulation of actin filament polymerization; axonogenesis; activation of MAPK activity; positive regulation of neuron apoptosis; MAPKKK cascade; dendrite development; mitotic cell cycle; actin cytoskeleton organization and biogenesis; protein amino acid phosphorylation
Research Articles on PAK3
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Product Notes
The Rat PAK3 pak3 (Catalog #AAA9343398) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9343398 ELISA Kit recognizes Rat PAK3. It is sometimes possible for the material contained within the vial of "p21 protein (Cdc42/Rac) -activated kinase 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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