Mouse protein arginine methyltransferase 1 ELISA Kit | PRMT1 elisa kit

Mouse Protein arginine N-methyltransferase 1, PRMT1 ELISA Kit

Cat. Num. AAA9341488

• Gene Names: Prmt1; Mrmt1; Hrmt1l2; AW214366; 6720434D09Rik
• Reactivity: Mouse
• Synonyms: protein arginine methyltransferase 1; Mouse Protein arginine N-methyltransferase 1; PRMT1 ELISA Kit; Mouse Protein arginine N-methyltransferase 1 (PRMT1) ELISA kit; ANM1; HCP1; HRMT1L2; IR1B4; HMT1 (hnRNP methyltransferase; S. cerevisiae) -like 2; HMT1 hnRNP methyltransferase-like 2; interferon receptor 1-bound protein 4; protein arginine N-methyltransferase 1; PRMT1 elisa kit

• Reactivity: Mouse
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Assay Type: Quantitative Sandwich
• Detection Range: 0.5 ng/ml - 16 ng/ml
• Sensitivity: 0.1 ng/ml
• Intra-assay Precision: Intra-assay CV(%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for PRMT1 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of PRMT1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 357197158
• NCBI GeneID: 15469
• NCBI Accession #: NP_001239405.1
• NCBI GenBank Nucleotide #: NM_001252476.1
• UniProt Accession #: Q9JIF0; Q99LS4
• Molecular Weight: 42,436 Da
• NCBI Official Full Name: protein arginine N-methyltransferase 1 isoform 2
• NCBI Official Synonym Full Names: protein arginine N-methyltransferase 1
• NCBI Official Symbol: Prmt1
• NCBI Official Synonym Symbols: Mrmt1; Hrmt1l2; AW214366; 6720434D09Rik
• NCBI Protein Information: protein arginine N-methyltransferase 1; histone-arginine N-methyltransferase PRMT1; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2
• UniProt Protein Name: Protein arginine N-methyltransferase 1
• Protein Family: Protein arginine N-methyltransferase
• UniProt Gene Name: Prmt1
• UniProt Synonym Gene Names: Hrmt1l2; Mrmt1
• UniProt Entry Name: ANM1_MOUSE

Uniprot Description

PRMT1: Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway. Homodimer and heterodimer with PRMT8. The dimer can then associate to form a homohexamer. Interacts with ILF3, BTG1, BTG2, SUPT5H and interferon-alpha/beta receptor 1. Interacts with NFATC2IP. Widely expressed. By BTG1, BTG2 and ILF3. Belongs to the protein arginine N-methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase; Methyltransferase, protein arginine; EC 2.1.1.125; Nuclear receptor co-regulator

Cellular Component: protein complex; cytoplasm; nucleus; cytosol

Molecular Function: identical protein binding; methyltransferase activity; trimethylamine methyltransferase activity; monomethylamine methyltransferase activity; RNA methyltransferase activity; tRNA (cytosine)-methyltransferase activity; rRNA (cytosine-C5-967)-methyltransferase activity; rRNA (uridine) methyltransferase activity; snoRNP binding; N-methyltransferase activity; tRNA (guanine) methyltransferase activity; rRNA (adenine-N6,N6-)-dimethyltransferase activity; selenocysteine methyltransferase activity; arginine N-methyltransferase activity; protein-arginine N-methyltransferase activity; methanol-specific methylcobalamin:coenzyme M methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; dimethylamine methyltransferase activity; [cytochrome c]-arginine N-methyltransferase activity; protein methyltransferase activity; 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity; hydroxyneurosporene-O-methyltransferase activity; transferase activity; rRNA (uridine-2'-O-)-methyltransferase activity; tRNA (uracil) methyltransferase activity; rRNA (adenine) methyltransferase activity; C-methyltransferase activity; cobalt-precorrin-6B C5-methyltransferase activity; cobalt-precorrin-3 C17-methyltransferase activity; 1-phenanthrol methyltransferase activity; S-methyltransferase activity; lysine N-methyltransferase activity; DNA-methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; tRNA (cytosine-5-)-methyltransferase activity; C-terminal protein carboxyl methyltransferase activity; tRNA (adenine)-methyltransferase activity; rRNA (cytosine) methyltransferase activity; cobalt-precorrin-7 C15-methyltransferase activity; protein-arginine N5-methyltransferase activity; rRNA methyltransferase activity; histone methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; histone-arginine N-methyltransferase activity; protein-leucine O-methyltransferase activity; demethylmenaquinone methyltransferase activity; rRNA (adenine-N6-)-methyltransferase activity; tRNA methyltransferase activity; rRNA (guanine) methyltransferase activity; methylarsonite methyltransferase activity; protein binding; mRNA methyltransferase activity; methylamine-specific methylcobalamin:coenzyme M methyltransferase activity; tRNA (guanine-N1-)-methyltransferase activity; cobalt-precorrin-5B C1-methyltransferase activity; protein-lysine N-methyltransferase activity; O-methyltransferase activity; tRNA (adenine-N1-)-methyltransferase activity; tRNA (adenine-57, 58-N(1)-) methyltransferase activity

Biological Process: methylation; histone methylation; peptidyl-arginine methylation; regulation of transcription, DNA-dependent; protein amino acid methylation; in utero embryonic development; peptidyl-arginine omega-N-methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; peptidyl-arginine N-methylation; negative regulation of megakaryocyte differentiation; neurite development