Human leucine-rich repeat-containing G protein-coupled receptor 6 ELISA Kit | LGR6 elisa kit
Human Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Description
LGR6: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A marker of adult stem cells. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. A marker of a multipotent population of skin stem cells. Three isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Tumor suppressor; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: nucleoplasm; integral to plasma membrane; cytoplasm; plasma membrane; trans-Golgi network membrane; vesicle
Molecular Function: G-protein coupled receptor activity; protein binding; transmembrane receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; Wnt receptor signaling pathway; positive regulation of Wnt receptor signaling pathway; positive regulation of cell migration
Research Articles on LGR6
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Product Notes
The Human LGR6 lgr6 (Catalog #AAA9338702) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338702 ELISA Kit recognizes Human LGR6. It is sometimes possible for the material contained within the vial of "leucine-rich repeat-containing G protein-coupled receptor 6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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