Mouse eukaryotic translation initiation factor 5A ELISA Kit | EIF5A elisa kit
Mouse Eukaryotic translation initiation factor 5A-1, EIF5A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an elongation initiation factor, which participates in protein synthesis. The encoded protein also plays roles in mRNA metabolism, cell proliferation, and cell cycle control. This protein contains a modified lysine residue called hypusine, which appears to be necessary for its function. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2, 5, and 19. [provided by RefSeq, Oct 2009]
Uniprot Description
EIF5A: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF- alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts. Belongs to the eIF-5A family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation; Translation initiation
Cellular Component: cell soma; membrane; endoplasmic reticulum; cytoplasm; dendrite; nuclear pore; nucleus; annulate lamellae
Molecular Function: RNA binding; ribosome binding; protein N-terminus binding; translation elongation factor activity; U6 snRNA binding
Biological Process: translational frameshifting; mRNA transport; translation; positive regulation of apoptosis; apoptosis; positive regulation of translational elongation; mRNA export from nucleus; protein transport; translational elongation; transport; positive regulation of cell proliferation; positive regulation of muscle cell differentiation; protein export from nucleus; positive regulation of translational termination; negative regulation of apoptosis
Research Articles on EIF5A
Similar Products
Product Notes
The Mouse EIF5A eif5a (Catalog #AAA9338390) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338390 ELISA Kit recognizes Mouse EIF5A. It is sometimes possible for the material contained within the vial of "eukaryotic translation initiation factor 5A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
