Mouse cholinergic receptor, nicotinic, beta 2 (neuronal) ELISA Kit | CHRNB2 elisa kit
Mouse Neuronal acetylcholine receptor subunit beta-2, CHRNB2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
nAChRB2: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNB2 are the cause of nocturnal frontal lobe epilepsy type 3 (ENFL3). ENFL3 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta- 2/CHRNB2 sub-subfamily.
Protein type: Membrane protein, multi-pass; Channel, cation; Channel, ligand-gated; Membrane protein, integral; Receptor, misc.
Cellular Component: nicotinic acetylcholine-gated receptor-channel complex; postsynaptic membrane; membrane; integral to membrane; plasma membrane; synapse; cell junction; external side of plasma membrane
Molecular Function: protein binding; protein heterodimerization activity; acetylcholine receptor activity; ion channel activity; drug binding; acetylcholine binding; nicotinic acetylcholine-activated cation-selective channel activity; extracellular ligand-gated ion channel activity
Biological Process: response to nicotine; positive regulation of dopamine secretion; protein heterooligomerization; regulation of dendrite morphogenesis; behavioral response to nicotine; locomotory behavior; regulation of circadian sleep/wake cycle, non-REM sleep; signal transduction; sensory perception of pain; regulation of dopamine secretion; synaptic transmission, cholinergic; smooth muscle contraction; regulation of synaptic transmission, dopaminergic; sensory perception of sound; visual perception; transport; conditioned taste aversion; calcium ion transport; positive regulation of B cell proliferation; visual learning; synaptic transmission involved in micturition; associative learning; regulation of circadian sleep/wake cycle, REM sleep; vestibulocochlear nerve development; regulation of action potential; B cell activation; central nervous system neuron axonogenesis; regulation of dopamine metabolic process; positive regulation of synaptic transmission, dopaminergic; central nervous system projection neuron axonogenesis; negative regulation of action potential; social behavior; learning; optic nerve morphogenesis; response to cocaine; memory; neurological system process; membrane depolarization; regulation of membrane potential; response to ethanol; regulation of synaptogenesis; response to hypoxia; ion transport; cognition; lateral geniculate nucleus development
Research Articles on CHRNB2
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Product Notes
The Mouse CHRNB2 chrnb2 (Catalog #AAA9338116) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9338116 ELISA Kit recognizes Mouse CHRNB2. It is sometimes possible for the material contained within the vial of "cholinergic receptor, nicotinic, beta 2 (neuronal), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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