Human purinergic receptor P2X, ligand-gated ion channel, 3 ELISA Kit | P2RX3 elisa kit
Human P2X purinoceptor 3, P2RX3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008]
Uniprot Description
P2X3: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Channel, ligand-gated
Chromosomal Location of Human Ortholog: 11q12
Cellular Component: Golgi apparatus; rough endoplasmic reticulum; cell soma; integral to plasma membrane; dendritic spine; terminal button; integral to nuclear inner membrane; receptor complex; lipid raft
Molecular Function: ATP binding; purinergic nucleotide receptor activity; ATP-gated cation channel activity
Biological Process: urinary bladder smooth muscle contraction; peristalsis; sensory perception of taste; generation of action potential; regulation of synaptic plasticity; positive regulation of calcium-mediated signaling; signal transduction; response to ATP; response to carbohydrate stimulus; behavioral response to pain; transport; response to mechanical stimulus; response to heat; response to hypoxia; neuromuscular synaptic transmission; response to cold; protein homooligomerization
Research Articles on P2RX3
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Product Notes
The Human P2RX3 p2rx3 (Catalog #AAA9337747) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337747 ELISA Kit recognizes Human P2RX3. It is sometimes possible for the material contained within the vial of "purinergic receptor P2X, ligand-gated ion channel, 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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