Mouse EDAR-associated death domain ELISA Kit | EDARADD elisa kit
Mouse Ectodysplasin-A receptor-associated adapter protein, EDARADD ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
EDARADD: Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF- kappa-B. Defects in EDARADD are a cause of ectodermal dysplasia anhidrotic (EDA); also known ectodermal dysplasia hypohidrotic autosomal recessive (HED). Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EDA is characterized by sparse hair (atrichosis or hypotrichosis), abnormal or missing teeth and the inability to sweat due to the absence of sweat glands. 2 isoforms of the human protein are produced by alternative splicing.
Cellular Component: cytoplasm
Molecular Function: protein binding; death receptor binding
Biological Process: I-kappaB kinase/NF-kappaB cascade; hair follicle development; multicellular organismal development; signal transduction; cell differentiation; odontogenesis of dentine-containing teeth
Disease: Ectodermal Dysplasia 10a, Hypohidrotic/hair/nail Type, Autosomal Dominant
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Product Notes
The Mouse EDARADD edaradd (Catalog #AAA9336549) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336549 ELISA Kit recognizes Mouse EDARADD. It is sometimes possible for the material contained within the vial of "EDAR-associated death domain, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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