Human synemin, intermediate filament protein ELISA Kit | SYNM elisa kit
Human Synemin, SYNM ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
DMN: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells. Belongs to the intermediate filament family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15q26.3
Cellular Component: adherens junction; costamere; membrane; neurofilament cytoskeleton; intermediate filament
Molecular Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle; intermediate filament binding; vinculin binding
Biological Process: intermediate filament cytoskeleton organization and biogenesis
Research Articles on SYNM
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Product Notes
The Human SYNM synm (Catalog #AAA9335890) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9335890 ELISA Kit recognizes Human SYNM. It is sometimes possible for the material contained within the vial of "synemin, intermediate filament protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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