Human WAS protein homolog associated with actin, golgi membranes and microtubules ELISA Kit | WHAMM elisa kit
Human WASP homolog-associated protein with actin, membranes and microtubules, WHAMM ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that plays a role in actin nucleation, Golgi membrane association and microtubule binding. The encoded protein is a nucleation-promoting factor that regulates the Actin-related protein 2/3 complex. The activated complex initiates growth of new actin filaments by binding to existing actin filaments. The encoded protein also functions in regulation of transport from the endoplasmic reticulum to the Golgi complex and in maintenance of the Golgi complex near the centrosome. Four pseudogenes of this gene are present on the same arm of chromosome 15 as this gene. [provided by RefSeq, Aug 2013]
Uniprot Description
WHAMM: Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Involved as a regulator of Golgi positioning and morphology. Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.
Chromosomal Location of Human Ortholog: 15q25.2
Cellular Component: Golgi membrane; microtubule; ER-Golgi intermediate compartment membrane; cytoplasmic vesicle membrane; cytoplasm
Molecular Function: microtubule binding; GTP-Rho binding; actin binding
Biological Process: focal adhesion formation; lamellipodium biogenesis; ER to Golgi vesicle-mediated transport; positive regulation of actin nucleation; actin filament organization
Research Articles on WHAMM
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Product Notes
The Human WHAMM whamm (Catalog #AAA9335691) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9335691 ELISA Kit recognizes Human WHAMM. It is sometimes possible for the material contained within the vial of "WAS protein homolog associated with actin, golgi membranes and microtubules, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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