Mouse SIN3 homolog A, transcription regulator (yeast) ELISA Kit | SIN3A elisa kit
Mouse Paired amphipathic helix protein Sin3a, SIN3A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SIN3A: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Interacts with BAZ2A, MXD3, MXD4, MBD2, NCOR1, NR4A2, REST, RLIM, SAP30, SETDB1 and SMYD2. Interacts with PHF12 in a complex composed of HDAC1, PHF12 and SAP30. Interacts with ARID4B, BRMS1L, DACH1, HCFC1, HDAC1, HDAC2, MXI1, SAP30L, SAP130, SFPQ, SUDS3 and TOPORS. Interacts with TET1; the interaction recruits SIN3A to gene promoters. Interacts with OGT (via TPRs 1-6); the interaction mediates transcriptional repression in parallel with histone deacetylase.
Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator; Nucleolus
Cellular Component: nucleoplasm; kinetochore; transcription factor complex; intercellular bridge; protein complex; Sin3 complex; transcriptional repressor complex; cytoplasm; chromatin; nucleus
Molecular Function: protein binding; DNA binding; RNA binding; protein deacetylase activity; protein complex binding; chromatin binding; histone deacetylase activity; transcription factor binding; transcription corepressor activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; positive regulation of chromatin silencing; transcription, DNA-dependent; in utero embryonic development; rhythmic process; histone deacetylation; negative regulation of transcription from RNA polymerase II promoter; response to organic nitrogen; regulation of transcription, DNA-dependent; protein amino acid deacetylation; response to methylglyoxal; hemopoietic progenitor cell differentiation; negative regulation of circadian rhythm; positive regulation of transcription from RNA polymerase II promoter; positive regulation of defense response to virus by host; DNA replication; negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter in response to oxidative stress; activation of innate immune response; negative regulation of apoptosis; aging
Research Articles on SIN3A
Similar Products
Product Notes
The Mouse SIN3A sin3a (Catalog #AAA9333529) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333529 ELISA Kit recognizes Mouse SIN3A. It is sometimes possible for the material contained within the vial of "SIN3 homolog A, transcription regulator (yeast), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
