Mouse ERO1-like beta (S. cerevisiae) ELISA Kit | ERO1LB elisa kit
Mouse ERO1-like protein beta, ERO1LB ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ERO1LB: Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress. Belongs to the EROs family.
Protein type: EC 1.8.4.-; Oxidoreductase; Endoplasmic reticulum
Cellular Component: membrane; cell; endoplasmic reticulum
Molecular Function: peptide-methionine-(S)-S-oxide reductase activity; protein disulfide isomerase activity; protein disulfide oxidoreductase activity; peptide-methionine (R)-S-oxide reductase activity; oxidoreductase activity; oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor
Biological Process: insulin processing; extracellular matrix organization and biogenesis; protein maturation via protein folding; 4-hydroxyproline metabolic process; cell redox homeostasis; transport; glucose homeostasis
Research Articles on ERO1LB
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Product Notes
The Mouse ERO1LB ero1lb (Catalog #AAA9332764) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9332764 ELISA Kit recognizes Mouse ERO1LB. It is sometimes possible for the material contained within the vial of "ERO1-like beta (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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