Mouse transmembrane protein 127 ELISA Kit | TMEM127 elisa kit
Mouse Transmembrane protein 127, TMEM127 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TMEM127: Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor. Defects in TMEM127 are a cause of susceptibility to pheochromocytoma (PCC). A catecholamine-producing tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of epinephrine and norepinephrine, is hypertension, which may be persistent or intermittent. Belongs to the TMEM127 family.
Protein type: Membrane protein, multi-pass; Tumor suppressor; Membrane protein, integral
Cellular Component: membrane; cytoplasm; early endosome; plasma membrane; integral to membrane
Molecular Function: Rab GTPase binding
Biological Process: negative regulation of cell proliferation; negative regulation of TOR signaling pathway; endosome organization and biogenesis; regulation of TOR signaling pathway
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Product Notes
The Mouse TMEM127 tmem127 (Catalog #AAA9331483) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331483 ELISA Kit recognizes Mouse TMEM127. It is sometimes possible for the material contained within the vial of "transmembrane protein 127, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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