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Mouse SET domain, bifurcated 2 ELISA Kit | SETDB2 elisa kit

Mouse Histone-lysine N-methyltransferase SETDB2, SETDB2 ELISA Kit

Gene Names
Setdb2; Clld8; Gm293; KMT1F
Reactivity
Mouse
Synonyms
SET domain; bifurcated 2; Mouse Histone-lysine N-methyltransferase SETDB2; SETDB2 ELISA Kit; Mouse Histone-lysine N-methyltransferase SETDB2 (SETDB2) ELISA kit; C13orf4; CLLD8; CLLL8; DKFZp586I0123; DKFZp761J1217; KMT1F; chronic lymphocytic leukemia deletion region 8; lysine N-methyltransferase 1F; SETDB2 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Assay Type
Quantitative Sandwich
Detection Range
0.625 ng/ml - 20 ng/ml
Sensitivity
0.1 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Related Product Information for SETDB2 elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of SETDB2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
80,636 Da
NCBI Official Full Name
histone-lysine N-methyltransferase SETDB2
NCBI Official Synonym Full Names
SET domain, bifurcated 2
NCBI Official Symbol
Setdb2
NCBI Official Synonym Symbols
Clld8; Gm293; KMT1F
NCBI Protein Information
histone-lysine N-methyltransferase SETDB2; Setdb2-Phf11-1-Phf11-2 fusion
UniProt Protein Name
Histone-lysine N-methyltransferase SETDB2
UniProt Gene Name
Setdb2
UniProt Synonym Gene Names
Gm293
UniProt Entry Name
SETB2_MOUSE

Uniprot Description

SETDB2: Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase; EC 2.1.1.43; Amino Acid Metabolism - lysine degradation; Methyltransferase, protein lysine

Cellular Component: chromosome; nucleus

Molecular Function: transferase activity; methyltransferase activity; DNA binding; zinc ion binding; metal ion binding; histone lysine N-methyltransferase activity (H3-K9 specific); histone-lysine N-methyltransferase activity

Biological Process: methylation; mitosis; cell division; multicellular organismal development; chromatin modification; cell cycle; histone H3-K9 methylation; peptidyl-lysine methylation; chromosome segregation

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Product Notes

The Mouse SETDB2 setdb2 (Catalog #AAA9331045) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331045 ELISA Kit recognizes Mouse SETDB2. It is sometimes possible for the material contained within the vial of "SET domain, bifurcated 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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