Mouse HIV-1 Tat interactive protein 2, 30kDa ELISA Kit | HTATIP2 elisa kit

Mouse Oxidoreductase HTATIP2, HTATIP2 ELISA Kit

Cat. Num. AAA9330308

• Gene Names: Htatip2; Cc3; Tip30; AW111545
• Reactivity: Mouse
• Synonyms: HIV-1 Tat interactive protein 2; 30kDa; Mouse Oxidoreductase HTATIP2; HTATIP2 ELISA Kit; Mouse Oxidoreductase HTATIP2 (HTATIP2) ELISA kit; CC3; FLJ26963; SDR44U1; TIP30; Tat-interacting protein (30kD) ; short chain dehydrogenase/reductase family 44U; member 1; HTATIP2 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 225690591
• NCBI GeneID: 53415
• NCBI Accession #: NP_001139521.1
• NCBI GenBank Nucleotide #: NM_001146049.1
• UniProt Accession #: Q9Z2G9; Q810Y5; Q99KN6; Q9D5F8; Q9D804
• Molecular Weight: 26,870 Da
• NCBI Official Full Name: oxidoreductase HTATIP2 isoform b
• NCBI Official Synonym Full Names: HIV-1 tat interactive protein 2, homolog (human)
• NCBI Official Symbol: Htatip2
• NCBI Official Synonym Symbols: Cc3; Tip30; AW111545
• NCBI Protein Information: oxidoreductase HTATIP2; tat-interacting protein 30 kDa; HIV-1 tat interactive protein 2, 30 kDa homolog
• UniProt Protein Name: Oxidoreductase HTATIP2
• Protein Family: Oxidoreductase
• UniProt Gene Name: Htatip2
• UniProt Synonym Gene Names: Cc3; Tip30
• UniProt Entry Name: HTAI2_MOUSE

Uniprot Description

HTATIP2: Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear envelope; Tumor suppressor; EC 1.1.1.-; Oxidoreductase; Apoptosis; Transcription factor

Cellular Component: membrane; cytoplasm; nuclear envelope; nucleus

Molecular Function: mevaldate reductase activity; (R)-2-hydroxyglutarate dehydrogenase activity; phenylcoumaran benzylic ether reductase activity; aldo-keto reductase activity; isocitrate dehydrogenase activity; arabinose reductase activity; oxidoreductase activity; C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity; epoxide dehydrogenase activity; protein serine/threonine kinase activity; (R)-2-hydroxyisocaproate dehydrogenase activity; steroid dehydrogenase activity; 3-ketoglucose-reductase activity; steroid dehydrogenase activity, acting on the CH-CH group of donors; D-arabinitol dehydrogenase (NADP+) activity; 2-hydroxytetrahydrofuran dehydrogenase activity; 5-exo-hydroxycamphor dehydrogenase activity; acetoin dehydrogenase activity; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; gluconate dehydrogenase activity; xylose reductase activity

Biological Process: positive regulation of programmed cell death; apoptosis; protein amino acid autophosphorylation; multicellular organismal development; nuclear import; angiogenesis; cell differentiation; regulation of angiogenesis; positive regulation of transcription from RNA polymerase II promoter, mitotic