Human GRINL1A complex locus ELISA Kit | GCOM1 elisa kit
Human GRINL1A complex locus protein 1, GCOM1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternative splicing results in multiple readthrough transcript variants. Readthrough variants may encode proteins that share sequence identity with the upstream gene product or with both the upstream and downstream gene products. Some readthrough transcript variants are also expected to be candidates for nonsense-mediated decay (NMD). [provided by RefSeq, Oct 2013]
Uniprot Description
GCOM1: Plays a role in cellular signaling via Rho-related GTP- binding proteins and subsequent activation of transcription factor SRF. Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1. Belongs to the MYZAP family. 11 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 15q21.3
Research Articles on GCOM1
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Product Notes
The Human GCOM1 myzap (Catalog #AAA9330099) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330099 ELISA Kit recognizes Human GCOM1. It is sometimes possible for the material contained within the vial of "GRINL1A complex locus, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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