Mouse NCK interacting protein with SH3 domain ELISA Kit | NCKIPSD elisa kit

Mouse NCK-interacting protein with SH3 domain, NCKIPSD ELISA Kit

Cat. Num. AAA9330064

• Gene Names: Nckipsd; DIP1; ORF1; WISH; Wasbp; AF3P21; SPIN90; WASLBP
• Reactivity: Mouse
• Synonyms: NCK interacting protein with SH3 domain; Mouse NCK-interacting protein with SH3 domain; NCKIPSD ELISA Kit; Mouse NCK-interacting protein with SH3 domain (NCKIPSD) ELISA kit; AF3P21; DIP; DIP1; MGC23891; ORF1; SPIN90; WASLBP; WISH; SH3 protein interacting with Nck; 90 kDa; dia interacting protein; diaphanous protein interacting protein; NCKIPSD elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 49258190
• NCBI GeneID: 80987
• NCBI Accession #: NP_109654.2
• NCBI GenBank Nucleotide #: NM_030729.4
• UniProt Accession #: Q9ESJ4; Q3UYF3; Q68G72
• Molecular Weight: 78,572 Da
• NCBI Official Full Name: NCK-interacting protein with SH3 domain
• NCBI Official Synonym Full Names: NCK interacting protein with SH3 domain
• NCBI Official Symbol: Nckipsd
• NCBI Official Synonym Symbols: DIP1; ORF1; WISH; Wasbp; AF3P21; SPIN90; WASLBP
• NCBI Protein Information: NCK-interacting protein with SH3 domain; VIP54; N-WASP-binding protein; SH3 adapter protein SPIN90; mDia interacting protein-1; 54 kDa VacA-interacting protein; 90 kDa N-WASP-interacting protein; WASP-interacting SH3-domain protein; 90 kDa SH3 protein interacting with Nck; Wiskott-Aldrich syndrome homolog binding protein; wiskott-Aldrich syndrome protein-binding protein WISH
• UniProt Protein Name: NCK-interacting protein with SH3 domain
• Protein Family: NCK-interacting protein with SH3 domain
• UniProt Gene Name: Nckipsd
• UniProt Synonym Gene Names: Spin90; Wasbp; VIP54; WISH; N-WASP-binding protein
• UniProt Entry Name: SPN90_MOUSE

Uniprot Description

NCKIPSD: Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo. In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42. May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis. A chromosomal aberration involving NCKIPSD/AF3p21 is found in therapy-related leukemia. Translocation t(3;11)(p21;q23) with MLL. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Oncoprotein; Motility/polarity/chemotaxis

Cellular Component: signalosome; nucleus

Molecular Function: SH3 domain binding