Human glycerate kinase ELISA Kit | GLYCTK elisa kit
Human Glycerate kinase, GLYCTK ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Uniprot Description
GLYCTK: Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA). D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Belongs to the glycerate kinase type-2 family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.1.31; Kinase, other; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - glycine, serine and threonine; Carbohydrate Metabolism - glyoxylate and dicarboxylate
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: mitochondrion; cytoplasm
Molecular Function: protein binding; glycerate kinase activity; ATP binding
Biological Process: protein amino acid phosphorylation
Disease: D-glyceric Aciduria
Research Articles on GLYCTK
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Product Notes
The Human GLYCTK glyctk (Catalog #AAA9329404) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329404 ELISA Kit recognizes Human GLYCTK. It is sometimes possible for the material contained within the vial of "glycerate kinase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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