Human solute carrier family 6 (neurotransmitter transporter, GABA) , member 1 ELISA Kit | SLC6A1 elisa kit

Human Sodium- and chloride-dependent GABA transporter 1, SLC6A1 ELISA Kit

Cat. Num. AAA9328323

• Gene Names: SLC6A1; GAT1; GABATR; GABATHG
• Reactivity: Human
• Synonyms: solute carrier family 6 (neurotransmitter transporter; GABA); member 1; Human Sodium- and chloride-dependent GABA transporter 1; SLC6A1 ELISA Kit; Human Sodium- and chloride-dependent GABA transporter 1 (SLC6A1) ELISA kit; GABATHG; GABATR; GAT1; ; SLC6A1 elisa kit

• Reactivity: Human

• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SLC6A1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of SLC6A1 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 188528618
• NCBI GeneID: 6529
• NCBI Accession #: NP_003033.3
• NCBI GenBank Nucleotide #: NM_003042.3
• UniProt Accession #: P30531; Q8N4K8
• Molecular Weight: 67,074 Da
• NCBI Official Full Name: sodium- and chloride-dependent GABA transporter 1
• NCBI Official Synonym Full Names: solute carrier family 6 (neurotransmitter transporter), member 1
• NCBI Official Symbol: SLC6A1
• NCBI Official Synonym Symbols: GAT1; GABATR; GABATHG
• NCBI Protein Information: sodium- and chloride-dependent GABA transporter 1; GAT-1; solute carrier family 6 member 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1
• UniProt Protein Name: Sodium- and chloride-dependent GABA transporter 1
• Protein Family: Sodium- and chloride-dependent GABA transporter
• UniProt Gene Name: SLC6A1
• UniProt Synonym Gene Names: GABATR; GABT1; GAT1; GAT-1
• UniProt Entry Name: SC6A1_HUMAN

NCBI Description

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009]

Uniprot Description

SLC6A1: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p25.3

Cellular Component: cell surface; membrane; axon; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: gamma-aminobutyric acid:sodium symporter activity; neurotransmitter:sodium symporter activity

Biological Process: response to purine; neurotransmitter secretion; response to toxin; learning; response to cocaine; response to estradiol stimulus; response to sucrose stimulus; synaptic transmission; transport; response to lead ion; gamma-aminobutyric acid import; negative regulation of synaptic transmission, GABAergic; response to calcium ion; transmembrane transport; protein homooligomerization; positive regulation of gamma-aminobutyric acid secretion

Disease: Myoclonic-atonic Epilepsy