Human splicing factor, arginine/serine-rich 5 ELISA Kit | SFRS5 elisa kit
Human Serine/arginine-rich splicing factor 5, SFRS5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2010]
Uniprot Description
SFRS5: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Belongs to the splicing factor SR family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Spliceosome; RNA-binding; RNA processing
Chromosomal Location of Human Ortholog: 14q24
Cellular Component: nucleoplasm; cytoplasm; nucleolus; nuclear speck; nucleus
Molecular Function: protein binding; RS domain binding; nucleotide binding
Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; mRNA splice site selection; mRNA export from nucleus; regulation of cell cycle; RNA splicing; response to wounding; gene expression; mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription
Research Articles on SFRS5
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Product Notes
The Human SFRS5 srsf5 (Catalog #AAA9326134) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9326134 ELISA Kit recognizes Human SFRS5. It is sometimes possible for the material contained within the vial of "splicing factor, arginine/serine-rich 5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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