Mouse farnesyltransferase, CAAX box, alpha ELISA Kit | FNTA elisa kit
Mouse Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, FNTA ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
FNTA: Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK. Belongs to the protein prenyltransferase subunit alpha family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.5.1.58; Transferase; EC 2.5.1.59
Cellular Component: microtubule associated complex; cytoplasm
Molecular Function: zinc ion binding; CAAX-protein geranylgeranyltransferase activity; microtubule binding; drug binding; receptor tyrosine kinase binding; peptide binding; protein prenyltransferase activity; protein farnesyltransferase activity; transferase activity; protein geranylgeranyltransferase activity; isoprenoid binding; acetylcholine receptor regulator activity; alpha-tubulin binding; Rab-protein geranylgeranyltransferase activity; prenyltransferase activity
Biological Process: protein geranylgeranylation; protein farnesylation; response to inorganic substance; protein prenylation; negative regulation of nitric-oxide synthase biosynthetic process; neurotransmitter receptor metabolic process; response to cytokine stimulus; positive regulation of cell proliferation; positive regulation of cell cycle; regulation of receptor activity; response to organic cyclic substance; negative regulation of apoptosis; positive regulation of nitric-oxide synthase biosynthetic process
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Product Notes
The Mouse FNTA fnta (Catalog #AAA9324058) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9324058 ELISA Kit recognizes Mouse FNTA. It is sometimes possible for the material contained within the vial of "farnesyltransferase, CAAX box, alpha, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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