Human transmembrane protein 188 ELISA Kit | TMEM188 elisa kit
Human Transmembrane protein 188, TMEM188 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transmembrane protein that belongs to the Tmemb_18A family. A similar protein in yeast is a component of an endoplasmic reticulum-associated protein phosphatase complex and is thought to play a role in the synthesis of triacylglycerol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Description
TMEM188: Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. Belongs to the CNEP1R1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 16q12.1
Cellular Component: nuclear membrane; cytoplasm; integral to membrane; nuclear envelope
Molecular Function: protein binding
Biological Process: mitotic nuclear envelope disassembly; lipid metabolic process; mitotic cell cycle; positive regulation of protein amino acid dephosphorylation
Research Articles on TMEM188
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Product Notes
The Human TMEM188 cnep1r1 (Catalog #AAA9323899) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323899 ELISA Kit recognizes Human TMEM188. It is sometimes possible for the material contained within the vial of "transmembrane protein 188, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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