Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Mouse suppressor of Ty 4 homolog 1 (S. cerevisiae) ELISA Kit | SUPT4H1 elisa kit

Mouse Transcription elongation factor SPT4, SUPT4H1 ELISA Kit

Gene Names
Supt4a; Supt4h; Supt4h1; AL022777; Supt4h1a
Reactivity
Mouse
Synonyms
suppressor of Ty 4 homolog 1 (S. cerevisiae); Mouse Transcription elongation factor SPT4; SUPT4H1 ELISA Kit; Mouse Transcription elongation factor SPT4 (SUPT4H1) ELISA kit; SPT4; SPT4H; SUPT4H; DRB sensitivity-inducing factor small subunit; DSIF p14; DSIF small subunit; suppressor of Ty 4 homolog 1; SUPT4H1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,193 Da
NCBI Official Full Name
transcription elongation factor SPT4-A
NCBI Official Synonym Full Names
suppressor of Ty 4A
NCBI Official Symbol
Supt4a
NCBI Official Synonym Symbols
Supt4h; Supt4h1; AL022777; Supt4h1a
NCBI Protein Information
transcription elongation factor SPT4-A; DSIF small subunit 1; suppressor of Ty 4 homolog 1; transcription elongation factor SPT4 1; DRB sensitivity-inducing factor small subunit 1
UniProt Protein Name
Transcription elongation factor SPT4-A
UniProt Gene Name
Supt4h1a
UniProt Synonym Gene Names
Spt4h; Supt4a; Supt4h; DSIF small subunit 1
UniProt Entry Name
SPT4A_MOUSE

Uniprot Description

SUPT4H1: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences. Belongs to the SPT4 family.

Cellular Component: nucleoplasm; nucleus

Molecular Function: zinc ion binding; protein heterodimerization activity; metal ion binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of RNA elongation; RNA elongation from RNA polymerase II promoter; negative regulation of RNA elongation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter

Research Articles on SUPT4H1

Similar Products

Product Notes

The Mouse SUPT4H1 supt4h1a (Catalog #AAA9323162) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323162 ELISA Kit recognizes Mouse SUPT4H1. It is sometimes possible for the material contained within the vial of "suppressor of Ty 4 homolog 1 (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.