Rat valosin-containing protein ELISA Kit | VCP elisa kit
Rat Transitional endoplasmic reticulum ATPase, VCP ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
ATP binding protein involved in vesicle transport and fusion; important for proper functioning of the endoplasmic reticulum [RGD, Feb 2006]
Uniprot Description
VCP: valosin-containing protein (VCP) is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. VCP, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the nuclear envelope and of the transitional endoplasmic reticulum (tER). Regulates NFKappaB pathway, which is important for metastasis of osteosarcoma. Tyrosine phosphorylation regulates its cell cycle-dependent nuclear localization.
Protein type: Chaperone; DNA repair, damage; EC 3.6.4.6; Endoplasmic reticulum; Hydrolase
Cellular Component: proteasome complex; nucleoplasm; endoplasmic reticulum membrane; protein complex; intracellular membrane-bound organelle; endoplasmic reticulum; perinuclear region of cytoplasm; cytoplasm; lipid particle; cytosol; nucleus; myelin sheath
Molecular Function: identical protein binding; protein domain specific binding; protein binding; ATPase activity; protein complex binding; ADP binding; polyubiquitin binding; protein phosphatase binding; lipid binding; ATP binding; receptor binding
Biological Process: ubiquitin-dependent protein catabolic process; caspase activation; ER to Golgi vesicle-mediated transport; ER-associated protein catabolic process; protein ubiquitination; retrograde protein transport, ER to cytosol; bypass DNA synthesis; positive regulation of protein complex assembly; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; double-strand break repair; positive regulation of protein catabolic process; protein amino acid N-linked glycosylation via asparagine; response to DNA damage stimulus; protein homooligomerization
Research Articles on VCP
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Product Notes
The Rat VCP vcp (Catalog #AAA9322723) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322723 ELISA Kit recognizes Rat VCP. It is sometimes possible for the material contained within the vial of "valosin-containing protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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