Mouse dachshund homolog 2 (Drosophila) ELISA Kit | DACH2 elisa kit
Mouse Dachshund homolog 2, DACH2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DACH2: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression. Probably binds to DNA via its DACHbox-N domain. Belongs to the DACH/dachshund family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Cellular Component: nucleus
Molecular Function: DNA binding
Biological Process: development of primary female sexual characteristics; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development
Research Articles on DACH2
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Product Notes
The Mouse DACH2 dach2 (Catalog #AAA9322322) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322322 ELISA Kit recognizes Mouse DACH2. It is sometimes possible for the material contained within the vial of "dachshund homolog 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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