Horse Relaxin/Insulin Like Family Peptide Receptor 1 ELISA Kit | RXFP1 elisa kit

Horse Relaxin/Insulin Like Family Peptide Receptor 1 ELISA Kit

Cat. Num. AAA44031

• Gene Names: RXFP2; LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2
• Reactivity: Horse
• Synonyms: Relaxin/Insulin Like Family Peptide Receptor 1; Horse Relaxin/Insulin Like Family Peptide Receptor 1 ELISA Kit; RXFP1 elisa kit

• Reactivity: Horse
• Sequence Length: 754

• Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids
• Detection Range: 31.2 pg/ml ~ 1000 pg/ml.
• Sensitivity: 5.0 pg/ml.
• Intended Uses: This ELISA kit is intended for laboratory in vitro research use only, not for drug, household or other use! The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm by a spectrophotometer. In order to measure the concentration of Horse RXFP1 in the sample, this ELISA kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus Horse RXFP1 concentration. The concentration of Horse RXFP1 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
• Intra-assay Precision: Intra-assay CV (%) are less than 15%.
• Inter-assay Precision: Inter-assay CV (%) are less than 15%.
• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 18677729
• NCBI GeneID: 122042
• NCBI Accession #: NP_570718.1
• NCBI GenBank Nucleotide #: NM_130806.3
• UniProt Accession #: Q8WXD0; Q3KU23; B1ALE9
• Molecular Weight: 86,453 Da
• NCBI Official Full Name: relaxin receptor 2 isoform 1
• NCBI Official Synonym Full Names: relaxin/insulin-like family peptide receptor 2
• NCBI Official Symbol: RXFP2
• NCBI Official Synonym Symbols: LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2
• NCBI Protein Information: relaxin receptor 2; G-protein coupled receptor 106; relaxin family peptide receptor 2; G protein coupled receptor affecting testicular descent; G-protein coupled receptor affecting testicular descent; leucine-rich repeat-containing G protein-coupled receptor 8; leucine-rich repeat-containing G-protein coupled receptor 8
• UniProt Protein Name: Relaxin receptor 2
• Protein Family: Relaxin receptor
• UniProt Gene Name: RXFP2
• UniProt Synonym Gene Names: GPR106; GREAT; LGR8
• UniProt Entry Name: RXFP2_HUMAN

NCBI Description

This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Uniprot Description

LGR8: the relaxin receptor is a G-protein coupled receptor (GPCR) that leads to the stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 13q13.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: peptide hormone binding; protein-hormone receptor activity

Biological Process: negative regulation of cell proliferation; positive regulation of cAMP biosynthetic process; male gonad development; G-protein signaling, adenylate cyclase inhibiting pathway; oocyte maturation; G-protein signaling, adenylate cyclase activating pathway; negative regulation of apoptosis

Disease: Cryptorchidism, Unilateral Or Bilateral