Mouse reversion-inducing-cysteine-rich protein with kazal motifs ELISA Kit | RECK elisa kit
Mouse Reversion-inducing cysteine-rich protein with Kazal motifs, RECK ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
RECK: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression. Interacts with MMP-9. Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.
Protein type: Membrane protein, GPI anchor; Tumor suppressor
Cellular Component: membrane; plasma membrane
Molecular Function: serine-type endopeptidase inhibitor activity; protease inhibitor activity; endopeptidase inhibitor activity
Biological Process: extracellular matrix organization and biogenesis; negative regulation of peptidase activity; blood vessel maturation; positive regulation of Notch signaling pathway; embryo implantation
Research Articles on RECK
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Product Notes
The Mouse RECK reck (Catalog #AAA9321601) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321601 ELISA Kit recognizes Mouse RECK. It is sometimes possible for the material contained within the vial of "reversion-inducing-cysteine-rich protein with kazal motifs, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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