Rat scaffold attachment factor B ELISA Kit | SAFB elisa kit
Rat Scaffold attachment factor B1, SAFB ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
interacts with RNA polymerase II and serine-arginine-rich RNA processing factors; may be a molecular base to assemble the transcriptosome complex [RGD, Feb 2006]
Uniprot Description
SAFB1: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing. Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter. Can inhibit cell proliferation.
Protein type: DNA-binding; Nuclear receptor co-regulator; RNA-binding
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; sequence-specific DNA binding; RNA binding; nucleotide binding; chromatin binding; protein kinase binding
Biological Process: regulation of transcription from RNA polymerase II promoter; estrogen receptor signaling pathway; transcription, DNA-dependent; hormone metabolic process; positive regulation of transcription from RNA polymerase II promoter; regulation of mRNA processing; growth
Research Articles on SAFB
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Product Notes
The Rat SAFB safb (Catalog #AAA9320997) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320997 ELISA Kit recognizes Rat SAFB. It is sometimes possible for the material contained within the vial of "scaffold attachment factor B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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