Human phosphatidylinositol glycan anchor biosynthesis, class B ELISA Kit | PIGB elisa kit
Human GPI mannosyltransferase 3, PIGB ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases. [provided by RefSeq, Jul 2008]
Uniprot Description
PIGB: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly. Belongs to the glycosyltransferase 22 family. PIGB subfamily.
Protein type: Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Endoplasmic reticulum; EC 2.4.1.-; Membrane protein, multi-pass; Transferase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 15q21.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: mannosyltransferase activity
Biological Process: cellular protein metabolic process; preassembly of GPI anchor in ER membrane; GPI anchor biosynthetic process; C-terminal protein lipidation; post-translational protein modification
Research Articles on PIGB
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Product Notes
The Human PIGB pigb (Catalog #AAA9320933) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320933 ELISA Kit recognizes Human PIGB. It is sometimes possible for the material contained within the vial of "phosphatidylinositol glycan anchor biosynthesis, class B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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