Mouse radical S-adenosyl methionine domain containing 2 ELISA Kit | RSAD2 elisa kit

Mouse Radical S-adenosyl methionine domain-containing protein 2, RSAD2 ELISA Kit

Cat. Num. AAA9319754

• Gene Names: Rsad2; Vig1; cig5; 2510004L01Rik
• Reactivity: Mouse
• Synonyms: radical S-adenosyl methionine domain containing 2; Mouse Radical S-adenosyl methionine domain-containing protein 2; RSAD2 ELISA Kit; Mouse Radical S-adenosyl methionine domain-containing protein 2 (RSAD2) ELISA kit; 2510004L01Rik; cig33; cig5; vig1; viperin; RSAD2 elisa kit

• Reactivity: Mouse

• Samples: Human Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) are less than 15%
• Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for RSAD2 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of RRAS2 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 31543946
• NCBI GeneID: 58185
• NCBI Accession #: NP_067359.2
• NCBI GenBank Nucleotide #: NM_021384.4
• UniProt Accession #: Q8CBB9; Q3U5I6; Q3U5T4; Q3U622; Q3U627; Q3U7I6; Q3U7M1; Q3U8F4; Q3U8U7; Q3U941; Q3U977; Q3U9E1
• Molecular Weight: 41,524 Da
• NCBI Official Full Name: radical S-adenosyl methionine domain-containing protein 2
• NCBI Official Synonym Full Names: radical S-adenosyl methionine domain containing 2
• NCBI Official Symbol: Rsad2
• NCBI Official Synonym Symbols: Vig1; cig5; 2510004L01Rik
• NCBI Protein Information: radical S-adenosyl methionine domain-containing protein 2; viperin; VHSV-induced-like protein; viral hemorrhagic septicemia virus (VHSV)-induced gene 1; virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible
• UniProt Protein Name: Radical S-adenosyl methionine domain-containing protein 2
• Protein Family: Radical S-adenosyl methionine domain-containing protein
• UniProt Gene Name: Rsad2
• UniProt Synonym Gene Names: Vig1
• UniProt Entry Name: RSAD2_MOUSE

Uniprot Description

RSAD2: Interferon-inducible iron-sulfur (4FE-4S) cluster- binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins. Belongs to the radical SAM superfamily. RSAD2 family.

Cellular Component: endoplasmic reticulum membrane; mitochondrial outer membrane; mitochondrion; membrane; endoplasmic reticulum; mitochondrial inner membrane; lipid particle

Molecular Function: protein binding; protein self-association; 4 iron, 4 sulfur cluster binding; metal ion binding; iron-sulfur cluster binding; catalytic activity

Biological Process: positive regulation of toll-like receptor 7 signaling pathway; negative regulation of protein secretion; ossification; CD4-positive, alpha beta T cell differentiation; negative regulation of viral genome replication; immune system process; response to virus; innate immune response; positive regulation of toll-like receptor 9 signaling pathway; regulation of ossification; defense response to virus