Mouse TAO kinase 1 ELISA Kit | TAOK1 elisa kit
Mouse Serine/threonine-protein kinase TAO1, TAOK1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TAO1: Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, STE; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; TAO subfamily
Cellular Component: cytoplasm
Molecular Function: transferase activity; protein serine/threonine kinase activity; MAP kinase kinase kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein kinase activator activity; protein kinase binding; ATP binding; protein kinase activity
Biological Process: activation of MAPKK activity; apoptosis; positive regulation of protein kinase activity; MAPKKK cascade; response to stress; positive regulation of JNK cascade; G2/M transition DNA damage checkpoint; DNA repair; response to DNA damage stimulus; phosphorylation; protein amino acid phosphorylation; positive regulation of stress-activated MAPK cascade; regulation of cytoskeleton organization and biogenesis
Research Articles on TAOK1
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Product Notes
The Mouse TAOK1 taok1 (Catalog #AAA9319535) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319535 ELISA Kit recognizes Mouse TAOK1. It is sometimes possible for the material contained within the vial of "TAO kinase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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