Mouse purinergic receptor P2Y, G-protein coupled, 12 ELISA Kit | P2RY12 elisa kit
Mouse P2Y purinoceptor 12, P2RY12 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
P2Y12: Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Involved in platelets aggregation. Defects in P2RY12 are the cause of bleeding disorder platelet-type 8 (BDPLT8). A condition characterized by mild to moderate mucocutaneous bleeding, and excessive bleeding after surgery or trauma. The defect is due to severe impairment of platelet response to ADP resulting in defective platelet aggregation. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Mitochondrial; Receptor, GPCR
Cellular Component: cell surface; mitochondrion; membrane; integral to plasma membrane; basal plasma membrane; plasma membrane; integral to membrane; intrinsic to membrane; caveola; external side of plasma membrane
Molecular Function: G-protein coupled receptor activity; signal transducer activity; purinergic nucleotide receptor activity, G-protein coupled; adenosine receptor activity, G-protein coupled; platelet ADP receptor activity
Biological Process: platelet activation; regulation of calcium ion transport; signal transduction; glial cell migration; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; negative regulation of cell differentiation; cell projection organization and biogenesis; hemostasis; protein kinase B signaling cascade; positive regulation of ion transport; G-protein signaling, adenylate cyclase inhibiting pathway; blood coagulation; adenosine receptor signaling pathway
Research Articles on P2RY12
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Product Notes
The Mouse P2RY12 p2ry12 (Catalog #AAA9319348) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319348 ELISA Kit recognizes Mouse P2RY12. It is sometimes possible for the material contained within the vial of "purinergic receptor P2Y, G-protein coupled, 12, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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