Mouse kelch-like 7 (Drosophila) ELISA Kit | KLHL7 elisa kit
Mouse Kelch-like protein 7, KLHL7 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
KLHL7: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination. Defects in KLHL7 are the cause of retinitis pigmentosa type 42 (RP42). A retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. 4 isoforms of the human protein are produced by alternative splicing.
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleolus; nucleus
Molecular Function: protein homodimerization activity
Biological Process: protein ubiquitination
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Product Notes
The Mouse KLHL7 klhl7 (Catalog #AAA9318880) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318880 ELISA Kit recognizes Mouse KLHL7. It is sometimes possible for the material contained within the vial of "kelch-like 7 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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