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Mouse extra spindle pole bodies homolog 1 (S. cerevisiae) ELISA Kit | ESPL1 elisa kit

Mouse Separin, ESPL1 ELISA Kit

Gene Names
Espl1; SSE; Cerp; ESP1; PRCE; AL024103; AU045071
Reactivity
Mouse
Synonyms
extra spindle pole bodies homolog 1 (S. cerevisiae); Mouse Separin; ESPL1 ELISA Kit; Mouse Separin (ESPL1) ELISA kit; ESP1; FLJ46492; KIAA0165; caspase-like protein ESPL1; extra spindle poles like 1; separase; separin; ESPL1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
233,035 Da
NCBI Official Full Name
separin
NCBI Official Synonym Full Names
extra spindle pole bodies 1 (S. cerevisiae)
NCBI Official Symbol
Espl1
NCBI Official Synonym Symbols
SSE; Cerp; ESP1; PRCE; AL024103; AU045071
NCBI Protein Information
separin; separase; Cut1/ESP1 related protein; caspase-like protein ESPL1; extra spindle poles-like 1 protein
UniProt Protein Name
Separin
Protein Family
UniProt Gene Name
Espl1
UniProt Synonym Gene Names
Esp1; Kiaa0165
UniProt Entry Name
ESPL1_MOUSE

Uniprot Description

separase: a caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. Regulated by at least two independent mechanisms. First, it is inactivated via its interaction with securin/PTTG1, which probably covers its active site. Second, phosphorylation inactivates it. It is completely phosphorylated during mitosis and dephosphorylated during anaphase. Two alternatively spliced isoforms have been described.

Protein type: EC 3.4.22.49; Protease

Cellular Component: centrosome; cytoplasm; nucleus

Molecular Function: peptidase activity; hydrolase activity; cysteine-type peptidase activity

Biological Process: mitosis; homologous chromosome segregation; mitotic sister chromatid segregation; proteolysis; meiotic spindle organization and biogenesis; meiosis I; chromosome segregation

Research Articles on ESPL1

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Product Notes

The Mouse ESPL1 espl1 (Catalog #AAA9318599) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318599 ELISA Kit recognizes Mouse ESPL1. It is sometimes possible for the material contained within the vial of "extra spindle pole bodies homolog 1 (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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