Mouse RNA binding motif protein 5 ELISA Kit | RBM5 elisa kit
Mouse RNA-binding protein 5, RBM5 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
RBM5: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. Belongs to the RBM5/RBM10 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA processing; Cell cycle regulation; Apoptosis; C2H2-type zinc finger protein; RNA splicing; RNA-binding
Cellular Component: nucleoplasm; spliceosome; nucleus
Molecular Function: mRNA binding; nucleic acid binding; zinc ion binding; RNA binding; metal ion binding; nucleotide binding
Biological Process: apoptosis; positive regulation of apoptosis; RNA splicing; spliceosome assembly; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome
Research Articles on RBM5
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Product Notes
The Mouse RBM5 rbm5 (Catalog #AAA9317862) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317862 ELISA Kit recognizes Mouse RBM5. It is sometimes possible for the material contained within the vial of "RNA binding motif protein 5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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