Mouse protein kinase, X-linked ELISA Kit | PRKX elisa kit
Mouse Serine/threonine-protein kinase PRKX, PRKX ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PRKX: Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation. A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein type: Protein kinase, AGC; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); AGC group; PKA family
Cellular Component: cytoplasm; nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; cAMP-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: regulation of cell adhesion; protein amino acid autophosphorylation; multicellular organismal development; protein amino acid phosphorylation; regulation of cell migration; cell-substrate adhesion; peptidyl-serine phosphorylation; endothelial cell proliferation; endothelial cell migration; myeloid cell differentiation; angiogenesis; cell differentiation; cell adhesion; phosphorylation
Research Articles on PRKX
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Product Notes
The Mouse PRKX prkx (Catalog #AAA9317783) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317783 ELISA Kit recognizes Mouse PRKX. It is sometimes possible for the material contained within the vial of "protein kinase, X-linked, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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