Human polo-like kinase 3 (Drosophila) ELISA Kit | PLK3 elisa kit
Human Serine/threonine-protein kinase PLK3, PLK3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
PLK3: a kinase of the PLK family. Phosphorylated and activated following DNA damage or mitotic spindle disruption. Interacts with Chk2 and the interaction is enhanced upon DNA damage. Apparent substrates include Chk2 and p53. Plays an important role in regulating microtubule dynamics and centrosomal function. Deregulated expression of Plk3 results in cell cycle arrest and apoptosis.
Protein type: Nucleolus; EC 2.7.11.21; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Other group; PLK family
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: centrosome; Golgi stack; cell soma; cytoplasm; dendrite; nucleolus; nucleus
Molecular Function: protein serine/threonine kinase activity; protein binding; p53 binding; ATP binding
Biological Process: apoptosis; mitotic cell cycle checkpoint; negative regulation of transcription from RNA polymerase II promoter; endomitotic cell cycle; response to osmotic stress; protein amino acid phosphorylation; regulation of cytokinesis; cytoplasmic microtubule organization and biogenesis; response to radiation; response to reactive oxygen species; protein kinase B signaling cascade; G2/M transition of mitotic cell cycle; response to DNA damage stimulus; regulation of cell division; G1/S transition of mitotic cell cycle; negative regulation of apoptosis
Research Articles on PLK3
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Product Notes
The Human PLK3 plk3 (Catalog #AAA9316126) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316126 ELISA Kit recognizes Human PLK3. It is sometimes possible for the material contained within the vial of "polo-like kinase 3 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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