Guinea Pig NPC1 (Niemann-Pick disease, type C1, gene) -like 1 ELISA Kit | NPC1L1 elisa kit

Guinea Pig Niemann-Pick C1-like protein 1, NPC1L1 ELISA Kit

• Reactivity: Guinea Pig
• Synonyms: NPC1 (Niemann-Pick disease; type C1; gene) -like 1; Guinea Pig Niemann-Pick C1-like protein 1; NPC1L1 ELISA Kit; Guinea pig Niemann-Pick C1-like protein 1 (NPC1L1) ELISA kit; NPC11L1; Niemann-Pick C1-like protein 1; NPC1L1 elisa kit

• Reactivity: Guinea Pig

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 50300485
• NCBI GeneID: 432367
• NCBI Accession #: NP_001002025.1
• NCBI GenBank Nucleotide #: NM_001002025.1
• UniProt Accession #: Q6T3U3
• Molecular Weight: 146,415 Da
• NCBI Official Full Name: Niemann-Pick C1-like protein 1
• NCBI Official Synonym Full Names: NPC1-like 1
• NCBI Official Symbol: Npc1l1
• NCBI Protein Information: Niemann-Pick C1-like protein 1; Niemann-Pick disease, type C1-like 1; NPC1 (Niemann-Pick disease, type C1, gene)-like 1
• UniProt Protein Name: Niemann-Pick C1-like protein 1
• Protein Family: Niemann-Pick C1-like protein
• UniProt Gene Name: Npc1l1
• UniProt Entry Name: NPCL1_RAT

NCBI Description

mouse homolog plays a role in intestinal cholesterol absorption [RGD, Feb 2006]

Uniprot Description

Function: Plays a major role in cholesterol homeostasis. Is critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption Lack of activity leads to multiple lipid transport defects. The protein may have a function in the transport of multiple lipids and their homeostasis. Acts as a negative regulator of NPC2 and down-regulates its expression and secretion by inhibiting its maturation and accelerating its degradation 1 PublicationManual assertion based on experiment in:Ref.3