Human integrin beta 4 binding protein (ITGB4BP) ELISA Kit | ITGB4BP elisa kit
Human integrin beta 4 binding protein, ITGB4BP ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Uniprot Description
EIF6: eukaryotic translation initiation factor 6. Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex.
Protein type: Translation initiation; Nucleolus; Translation
Chromosomal Location of Human Ortholog: 20q12
Cellular Component: nucleoplasm; cytoplasm; lamin filament; nucleolus; nucleus
Molecular Function: protein binding; translation initiation factor activity; ribosome binding; ribosomal large subunit binding
Biological Process: translational initiation; ribosomal large subunit biogenesis and assembly; mature ribosome assembly; ribosome export from nucleus
Research Articles on ITGB4BP
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Product Notes
The Human ITGB4BP eif6 (Catalog #AAA9310872) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9310872 ELISA Kit recognizes Human ITGB4BP. It is sometimes possible for the material contained within the vial of "integrin beta 4 binding protein (ITGB4BP), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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