Mouse Sialidase-1, NEU1 ELISA Kit | NEU1 elisa kit
Mouse Sialidase-1, NEU1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NEU1: Catalyzes the removal of sialic acid (N-acetylneuramic acid) moities from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage. Defects in NEU1 are the cause of sialidosis (SIALIDOSIS). It is a lysosomal storage disease occurring as two types with various manifestations. Type 1 sialidosis (cherry red spot-myoclonus syndrome or normosomatic type) is late-onset and it is characterized by the formation of cherry red macular spots in childhood, progressive debilitating myoclonus, insiduous visual loss and rarely ataxia. The diagnosis can be confirmed by the screening of the urine for sialyloligosaccharides. Type 2 sialidosis (also known as dysmorphic type) occurs as several variants of increasing severity with earlier age of onset. It is characterized by the presence of abnormal somatic features including coarse facies and dysostosis multiplex, vertebral deformities, mental retardation, cherry-red spot/myoclonus, sialuria, cytoplasmic vacuolation of peripheral lymphocytes, bone marrow cells and conjunctival epithelial cells. Belongs to the glycosyl hydrolase 33 family.
Protein type: EC 3.2.1.18; Lipid Metabolism - sphingolipid; Motility/polarity/chemotaxis; Hydrolase; Glycan Metabolism - other glycan degradation
Cellular Component: cell surface; intracellular membrane-bound organelle; membrane; lysosome; plasma membrane; cytoplasmic vesicle; cell junction
Molecular Function: protein binding; hydrolase activity; hydrolase activity, acting on glycosyl bonds; exo-alpha-sialidase activity
Biological Process: oligosaccharide catabolic process; metabolic process; carbohydrate metabolic process; lipid metabolic process; lipid catabolic process
Research Articles on NEU1
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Product Notes
The Mouse NEU1 neu1 (Catalog #AAA9305489) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9305489 ELISA Kit recognizes Mouse NEU1. It is sometimes possible for the material contained within the vial of "Sialidase-1, NEU1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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