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Western Blot (WB) (Anti-GDF11 Antibody at 1:2000 dilution + GDF11 recombinant proteinLysates/proteins at 20 ng per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Mouse GDF11 Monoclonal Antibody | anti-GDF11 antibody

GDF11 Antibody

Gene Names
GDF11; BMP11; BMP-11
Reactivity
Human
Predicted: Human
Applications
Western Blot, ELISA
Purity
Purified through a protein G column, followed by dialysis against PBS.
Synonyms
GDF11; Monoclonal Antibody; GDF11 Antibody; Purified Mouse Monoclonal Antibody (Mab); Growth/differentiation factor 11; GDF-11; Bone morphogenetic protein 11; BMP-11; BMP11; anti-GDF11 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Predicted: Human
Clonality
Monoclonal
Isotype
IgG1,kappa
Clone Number
1956CT308.38.25
Specificity
This GDF11 antibody is generated from a mouse immunized with a recombinant protein from the human region of human GDF11.
Purity/Purification
Purified through a protein G column, followed by dialysis against PBS.
Form/Format
Supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Length
407
Applicable Applications for anti-GDF11 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:2000
Antigen Type
Synthesized Peptide
Antigen Source
Human
Cellular Location
Secreted.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks.
For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-GDF11 Antibody at 1:2000 dilution + GDF11 recombinant proteinLysates/proteins at 20 ng per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-GDF11 Antibody at 1:2000 dilution + GDF11 recombinant proteinLysates/proteins at 20 ng per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-GDF11 antibody
Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Product Categories/Family for anti-GDF11 antibody
References
Gamer L.W.,et al.Dev. Biol. 208:222-232(1999). McPherron A.C.,et al.Nat. Genet. 22:260-264(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45091
NCBI Official Full Name
growth/differentiation factor 11 preproprotein
NCBI Official Synonym Full Names
growth differentiation factor 11
NCBI Official Symbol
GDF11
NCBI Official Synonym Symbols
BMP11; BMP-11
NCBI Protein Information
growth/differentiation factor 11
UniProt Protein Name
Growth/differentiation factor 11
UniProt Gene Name
GDF11
UniProt Synonym Gene Names
; BMP-11

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]

Uniprot Description

Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634).

Research Articles on GDF11

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Product Notes

The GDF11 gdf11 (Catalog #AAA9231316) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GDF11 Antibody reacts with Human Predicted: Human and may cross-react with other species as described in the data sheet. AAA Biotech's GDF11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:2000. Researchers should empirically determine the suitability of the GDF11 gdf11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDF11, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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