RAP2A blocking peptide
RAP2A Blocking Peptide (C-Term)
Gene Names
RAP2A; KREV; RAP2; K-REV; RbBP-30
Synonyms
RAP2A; RAP2A Blocking Peptide (C-Term); Ras-related protein Rap-2a; RbBP-30; RAP2A blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 144-159 of HUMAN RAP2A
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
183
Cellular Location
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. Note: May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995). Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for RAP2A blocking peptide
Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
20,615 Da
NCBI Official Full Name
Ras-related protein Rap-2a
NCBI Official Synonym Full Names
RAP2A, member of RAS oncogene family
NCBI Official Symbol
RAP2A
NCBI Official Synonym Symbols
KREV; RAP2; K-REV; RbBP-30
NCBI Protein Information
ras-related protein Rap-2a
UniProt Protein Name
Ras-related protein Rap-2a
Protein Family
UniProt Gene Name
RAP2A
UniProt Entry Name
RAP2A_HUMAN
Uniprot Description
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Research Articles on RAP2A
Similar Products
Product Notes
The RAP2A rap2a (Catalog #AAA9230320) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RAP2A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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