M Tfap2c Blocking Peptide | Tfap2c blocking peptide

M Tfap2c Blocking Peptide (N-term)

• Gene Names: Tfap2c; Stra2; Ap-2.2; Tcfap2c; AA409384; AP2gamma
• Synonyms: M Tfap2c; M Tfap2c Blocking Peptide (N-term); Transcription factor AP-2 gamma; AP2-gamma; AP-22; Activating enhancer-binding protein 2 gamma; Tfap2c; Tcfap2c; Tfap2c blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 133-144 of Mouse Tfap2c
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 449

• Cellular Location: Nucleus.
• Tissue Location: Expressed in lung, ovary and testis. Expressed in most squamous epithelia. Also, detected in several exocrine glands including the prostate, the preputial and salivary glands, serous glands of the tongue and ocular harderian glands
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for Tfap2c blocking peptide

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

NCBI and Uniprot Product Information

• NCBI GI #: 341940232
• NCBI GeneID: 21420
• UniProt Accession #: Q61312; Q99L72
• Molecular Weight: 49,137 Da
• NCBI Official Full Name: Transcription factor AP-2 gamma
• NCBI Official Synonym Full Names: transcription factor AP-2, gamma
• NCBI Official Symbol: Tfap2c
• NCBI Official Synonym Symbols: Stra2; Ap-2.2; Tcfap2c; AA409384; AP2gamma
• NCBI Protein Information: transcription factor AP-2 gamma
• UniProt Protein Name: Transcription factor AP-2 gamma
• Protein Family: Transcription factor
• UniProt Gene Name: Tfap2c
• UniProt Synonym Gene Names: Tcfap2c; AP2-gamma
• UniProt Entry Name: AP2C_MOUSE

Uniprot Description

AP-2 gamma: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with KCTD1; this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the interaction stimulates TFAP2B-transcriptional activity. During retinoic acid-mediated differentiation. Belongs to the AP-2 family.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor

Cellular Component: mitochondrion; nucleoplasm; nucleus

Molecular Function: DNA binding; protein binding; protein dimerization activity; transcription factor activity

Biological Process: cell differentiation; cerebral cortex development; forebrain neuron fate commitment; germ-line stem cell maintenance; hair follicle development; positive regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation; regulation of epidermis development; regulation of gene expression, epigenetic; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; sebaceous gland development; skin development; somatic stem cell maintenance; stem cell maintenance; trophectodermal cell differentiation