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SC11A Blocking Peptide | SEC11A blocking peptide

SC11A Blocking Peptide (Center)

Gene Names
SEC11A; SPC18; SPCS4A; SEC11L1; sid2895; 1810012E07Rik
Synonyms
SC11A; SC11A Blocking Peptide (Center); Signal peptidase complex catalytic subunit SEC11A; Endopeptidase SP18; Microsomal signal peptidase 18 kDa subunit; SPase 18 kDa subunit; SEC11 homolog A; SEC11-like protein 1; SPC18; SEC11A; SEC11L1; SPCS4A; SEC11A blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 110-123 of HUMAN SEC11A
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
179
Cellular Location
Microsome membrane; Single- pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SEC11A blocking peptide
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,988 Da
NCBI Official Full Name
signal peptidase complex catalytic subunit SEC11A isoform 2
NCBI Official Synonym Full Names
SEC11 homolog A, signal peptidase complex subunit
NCBI Official Symbol
SEC11A
NCBI Official Synonym Symbols
SPC18; SPCS4A; SEC11L1; sid2895; 1810012E07Rik
NCBI Protein Information
signal peptidase complex catalytic subunit SEC11A
UniProt Protein Name
Signal peptidase complex catalytic subunit SEC11A
Protein Family
UniProt Gene Name
SEC11A
UniProt Synonym Gene Names
SEC11L1; SPC18; SPCS4A; SPase 18 kDa subunit
UniProt Entry Name
SC11A_HUMAN

NCBI Description

This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Dec 2012]

Uniprot Description

SEC11A: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the peptidase S26B family.

Protein type: Membrane protein, integral; EC 3.4.21.89; Protease

Chromosomal Location of Human Ortholog: 15q25.3

Cellular Component: endoplasmic reticulum membrane

Research Articles on SEC11A

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Product Notes

The SEC11A sec11a (Catalog #AAA9228814) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SC11A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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