ELOVL5 blocking peptide

ELOVL5 Antibody (C-term) Blocking Peptide

• Gene Names: ELOVL5; HELO1; SCA38; dJ483K16.1
• Synonyms: ELOVL5; ELOVL5 Antibody (C-term) Blocking Peptide; Elongation of very long chain fatty acids protein 5; 3-keto acyl-CoA synthase ELOVL5; ELOVL fatty acid elongase 5; ELOVL FA elongase 5; Fatty acid elongase 1; hELO1; Very-long-chain 3-oxoacyl-CoA synthase 5; ELOVL2; ELOVL5 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 299

• Cellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein Cytoplasm. Cell projection. Cell projection, dendrite Note: In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree
• Tissue Location: Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain Expressed in the cerebellum.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ELOVL5 blocking peptide

Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.

NCBI and Uniprot Product Information

• NCBI GI #: 74753072
• NCBI GeneID: 60481
• UniProt Accession #: Q9NYP7; Q59EL3; Q5TGH5; Q6NXE7; Q7L2S5; Q8NCG4; Q9UI22; B4DZJ2; F6SH78
• Molecular Weight: 9,580 Da
• NCBI Official Full Name: Elongation of very long chain fatty acids protein 5
• NCBI Official Synonym Full Names: ELOVL fatty acid elongase 5
• NCBI Official Symbol: ELOVL5
• NCBI Official Synonym Symbols: HELO1; SCA38; dJ483K16.1
• NCBI Protein Information: elongation of very long chain fatty acids protein 5
• UniProt Protein Name: Elongation of very long chain fatty acids protein 5
• UniProt Gene Name: ELOVL5
• UniProt Synonym Gene Names: ELOVL FA elongase 5; hELO1
• UniProt Entry Name: ELOV5_HUMAN

NCBI Description

This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Uniprot Description

ELOVL5: Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Belongs to the ELO family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; EC 2.3.1.199; Lipid Metabolism - unsaturated fatty acid biosynthesis

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: cell soma; endoplasmic reticulum; endoplasmic reticulum membrane; membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: linoleic acid metabolic process; very-long-chain fatty acid biosynthetic process

Disease: Spinocerebellar Ataxia 38