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FCGR1B blocking peptide

FCGR1B Antibody (C-term) Blocking Peptide

Gene Names
FCGR1B; CD64b; IGFRB
Synonyms
FCGR1B; FCGR1B Antibody (C-term) Blocking Peptide; High affinity immunoglobulin gamma Fc receptor IB; IgG Fc receptor IB; Fc-gamma RIB; FcRIB; hFcgammaRIB; IGFRB; FCGR1B blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human FCGR1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
280
Cellular Location
Cell membrane; Single-pass type I membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for FCGR1B blocking peptide
May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22,136 Da
NCBI Official Full Name
High affinity immunoglobulin gamma Fc receptor IB
NCBI Official Synonym Full Names
Fc fragment of IgG receptor Ib
NCBI Official Symbol
FCGR1B
NCBI Official Synonym Symbols
CD64b; IGFRB
NCBI Protein Information
high affinity immunoglobulin gamma Fc receptor IB
UniProt Protein Name
High affinity immunoglobulin gamma Fc receptor IB
UniProt Gene Name
FCGR1B
UniProt Synonym Gene Names
IGFRB; IgG Fc receptor IB; FcRIB; hFcgammaRIB
UniProt Entry Name
FCGRB_HUMAN

NCBI Description

Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

FCGR1B: May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response. Belongs to the immunoglobulin superfamily. FCGR1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p11.2

Cellular Component: early endosome membrane; plasma membrane

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; receptor-mediated endocytosis

Research Articles on FCGR1B

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Product Notes

The FCGR1B fcgr1b (Catalog #AAA9228073) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "FCGR1B, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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