LRRC16A blocking peptide
LRRC16A Antibody (C-term) Blocking Peptide
NCBI and Uniprot Product Information
Uniprot Description
LRRC16: Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization. Belongs to the CARMIL family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 6p22.2
Cellular Component: cytoplasm; cytosol; filamentous actin; lamellipodium; leading edge; nucleus; plasma membrane
Molecular Function: protein binding; protein complex binding
Biological Process: actin filament network formation; barbed-end actin filament uncapping; blood coagulation; cell migration; lamellipodium biogenesis; positive regulation of actin filament polymerization; positive regulation of cell migration; positive regulation of stress fiber formation; ruffle organization and biogenesis; urate metabolic process
Research Articles on LRRC16A
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Product Notes
The LRRC16A lrrc16a (Catalog #AAA9223262) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LRRC16A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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